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Atlas of Blood Cells and Blood Disease

Atlas on integrated diagnosis in hematology, Project directed by Dra. Teresa Vallespí and Dr. Luis García - www.atlasbloodcells.es © 2012

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Immunoglobulin M (IgM) multiple myeloma versus Waldenström macroglobulinemia: diagnostic challenges and therapeutic options: two case reports

Autors:  Simona Elba ,  Alessia Castellino ,  […] Massimo Massaia volume details Abstract Background Immunoglobulin M multiple myeloma and Waldenström macroglobulinemia are two different hematological diseases with the common finding of an immunoglobulin M monoclonal gammopathy of unknown significance. However, clinical characteristics of the two entities can overlap. Case presentation In this report, we describe two cases of immunoglobulin M neoplasm with the same histological bone marrow presentation but with different clinical behavior, cytogenetics, and biological assessment. On the basis of comprehensive diagnostic workup, these patients were considered to have different diseases and treated accordingly with different approaches. Patient 1 (Caucasian man) presented with increased serum protein and immunoglobulin M (7665 mg/L) with an M-spike electrophoresis of 4600 mg/L. His bone marrow biopsy revealed a small-cell immunoglobulin M mul...
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E-Learning Library By Clinical Cytometry Education Network (CCEN)

E-Learning Library Internet-based technology is capable of addressing many of the challenges faced in providing global flow cytometry education. According, we strive to expand the availabilty of web-based educational materials and to build a comprehensive electronic library including: Online Courses A collection of formal presentations from invited experts covering a broad range of clinical cytometry topics.  Slide-based presentations will be supplemented with notes, audio, video, or real-time interaction (webinar).  Short Instructional Videos Short, 5 – 15 minute, videos addressing practical aspects of clinical flow cytometry, including identification of individual cells, an approach to the diagnosis of specific disease entities, how to avoid pitfalls, and technical tips.   Clinical Case Studies A comprehensive portfolio of clinical case studies with provision of relevant clinical information, the results of other laboratory testing, and raw cytometry data thro...